Bioanalytical method development
Bioanalysis in the department has traditionally focused on anti-malaria drugs, with more than 20 bioanalytical methods in use currently. We have broadened the scope of applications to include a variety of antibiotics, antiviral and anti-parasitic drugs. Besides anti-tuberculosis drugs, we have validated and implemented methods for ivermectin and ceftriaxone into routine bioanalysis. Particular focus has been directed towards developing assays for field-adapted pharmacokinetic sampling methodologies (i.e. capillary blood spot assays).