Mathematical and Economic Modelling (MAEMOD)
The Mathematical and Economic MODelling (MAEMOD) Department’s main research focus is mathematical and economic models supporting investigations into the transmission, control and elimination of tropical diseases.
Led by Acting Head Wirichada Pan-ngum MAEMOD uses mathematical and economic models to support investigations into the transmission, control and elimination of tropical diseases in the Greater Mekong Sub-Region (GMS). MAEMOD's active policy engagement with governments, stakeholders and communities helps us identify the right research questions, implement pragmatic, data driven solutions and evaluate them in the field for impact and effectiveness.
Led by Asst Prof Wirichada Pan-ngum, Acting Head, MAEMOD, the Neglected Tropical Diseases Modelling (NTDM) Group focuses on regional health problems, mostly neglected tropical diseases such as leptospirosis, melioidosis, dengue, and tuberculosis.
A cross-cutting research group based at MAEMOD with members throughout the MORU network, including in Cambodia (COMRU) and Lao PDR (LOMWRU), the Bacterial Resistance Analysis Group (BRAG) is led by Prof Ben Cooper.
Led by Assoc Prof Yoel Lubell, the Economics and Implementation Research Group’s main remit is to explore the cost-effectiveness of diagnostics, treatments and vaccines for infectious diseases. The multidisciplinary group reflects the nature of its broad focus, going beyond clinical efficacy to encompass how interventions can achieve high impact in routine care environments, considering contextual barriers to their implementation.
Led by Research Fellow Dr Ricardo Aguas, the AToME (Analytical Tools for Malaria Elimination) Group is currently entirely dedicated to the Enhanced modelling for NMCP Decision-making to Accelerate Malaria Elimination (ENDGAME) project, funded by the Bill and Melinda Gates Foundation. Engaging with National Malaria Control Programmes (NMCP) in the Greater Mekong Sub-Region (GMS), ENDGAME calibrates malaria transmission models using epidemiological data and records from previous intervention deployments to predict the impact and cost efficiency of different elimination driven strategies.
Since 2015, MAEMOD has led, supported or contributed to a number of teaching, training and capacity building initiatives, research projects, public engagement activities, and scientific publications, many of them on-going and with a significant impact on the transmission, control and elimination of tropical diseases. MAEMOD currently has 7 PhD/DPhil students and 2 DPhil candidates at the Nuffield Department of Medicine, University of Oxford. Students from the Oxford IHTM MSc course have successfully completed their placements with MAEMOD projects, many of which have culminated in their first academic papers. Since 2015, members of MAEMOD have contributed to 133 publications, 31 of them in 2019 to date.
MAEMOD’s vision remains to provide pragmatic high technology solutions in resource poor settings. We will apply appropriate cutting-edge mathematical and economic methodologies to accelerate the delivery of the life-saving clinical research conducted at MORU to those who need it most. We plan to expand our capacity building programme abroad and in Thailand, where it has resulted in increased engagement with Thai government partners.