Phornpimon Tipthara

Phornpimon is Deputy Head of Discovery at the Department of Clinical Pharmacology, Mahidol Oxford Tropical Medicine Research Unit (MORU). Her research focuses on the application of high-resolution mass spectrometry–based technologies, including untargeted metabolomics, lipidomics, and proteomics, to study mechanisms of drug action, understand disease pathophysiology, and improve diagnostics for tropical diseases. Her work combines omics technologies with translational pharmacology to identify biomarkers, characterise host–pathogen–drug interactions, and improve understanding of disease mechanisms in infectious diseases.

Her research expertise also includes drug metabolism studies, such as drug metabolite identification, biotransformation, and in vitro assays for investigating drug metabolism, drug transporters, and drug–drug interactions. She has experience working with microsomes and recombinant cytochrome P450 enzymes, and is interested in generating in vitro data for physiologically based pharmacokinetic (PBPK) modeling.

Another area of her research is the development of dried blood spot (DBS) metabolomics approaches, which may help improve access to diagnostic and monitoring tools in resource-limited settings. By combining analytical chemistry, pharmacology, and systems biology, her work aims to support individualized medicine and strengthen tropical disease research and clinical applications.