Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

A rapidly evolving multi-drug resistant lineage of P. falciparum malaria parasites continues to spread in South East Asia, leading to alarmingly high treatment failure rates in Cambodia, Thailand and Vietnam for DHA-piperaquine, one of the world’s most important anti-malaria drugs.

None © CDC James Gathany

DHA-piperaquine should no longer be used to treat falciparum malaria in Cambodia, Vietnam and northeast Thailand as it is ineffective and thereby contributes to increased malaria transmission, according to University of Oxford researchers in a study published in The Lancet Infectious Diseases.

The researchers called for urgent action to eliminate falciparum malaria from the Greater Mekong Subregion to prevent local increase of these multiple resistant strains and their further spread to other parts of Asia and Africa and avoid a potential global health emergency.

Read more (Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine)

Similar stories

Simple new method that measures viral clearance means antibody treatments for COVID and ‘flu can be quickly assessed for effectiveness, say MORU researchers

Measuring the rate of viral clearance from the back of the mouth in patients with mild infections can be used to determine quickly and inexpensively if an antibody is effective in future COVID-19, influenza and other respiratory virus pandemics, say researchers in a letter published today in The Lancet.