James Callery is a British medical doctor who has worked as a Research Physician within the Malaria Department at the Mahidol Oxford Tropical Medicine Research Unit (MORU) in Thailand since 2017.
At MORU James has worked as co-investigator and Research Physician on the TACT-CV study, a multicentre therapeutic efficacy and safety trial in Southeast Asia, comparing artemether-lumefantrine (ACT) with artemether-lumefantrine plus amodiaquine (Triple ACT) for the treatment of uncomplicated falciparum malaria. He has been running and monitoring the study sites in Cambodia whilst working in close collaboration with colleagues across the Greater Mekong Subregion (GMS).
With the development and spread of multi-drug resistant malaria parasites, this novel combination therapy could play an important role in the efforts to eliminate malaria from the GMS.
Since 2018, James has also coordinated large public engagement projects in Northeastern Cambodia. These events aim to engage the local community with malaria prevention and other health awareness campaigns.
James’ main research interest is focussed on the development and evaluation of novel malaria intervention strategies to aid elimination efforts in the GMS. The TACT-CV study will be completed in early 2020 and James has already begun work on a new clinical trial evaluating ACTs as malaria prophylaxis in Cambodian forest-goers.
Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial
van der Pluijm RW. et al, (2020), The Lancet, 395, 1345 - 1360
Forest work and its implications for malaria elimination: a qualitative study
Sanann N. et al, (2019), Malaria Journal, 18
How can interventions that target forest-goers be tailored to accelerate malaria elimination in the Greater Mekong Subregion? A systematic review of the qualitative literature
Nofal SD. et al, (2019), Malaria Journal, 18
The feasibility and acceptability of mass drug administration for malaria in Cambodia: a mixed-methods study
Peto TJ. et al, (2018), Transactions of The Royal Society of Tropical Medicine and Hygiene, 112, 264 - 271