Dr Cindy Chu
Contact information
Cindy Chu
Clinical researcher
Cindy’s main research area is in Plasmodium vivax malaria. She has conducted studies on the epidemiology of P. vivax recurrence as well as efficacy trials with the schizonticidal agents chloroquine and dihydroartemisinin-piperaquine. Her current focus is on the radical curative treatment of P. vivax using 8-aminoquinolines and the haemolytic effects of this class of drugs in G6PD heterozygous females. The goal of this research is for the safe delivery of primaquine and tafenoquine for treatment of P. vivax malaria and within the context of P. vivax elimination.
Chloroquine and primaquine induced haematocrit changes to G6PD heterozygote
Plasmodium vivax recurrences
Key publications
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Primaquine-induced haemolysis in females heterozygous for G6PD deficiency
Journal article
Chu CS. et al, (2018), Malaria Journal, 17
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Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria.
Journal article
Llanos-Cuentas A. et al, (2019), The New England journal of medicine, 380, 229 - 241
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Comparison of the Cumulative Efficacy and Safety of Chloroquine, Artesunate, and Chloroquine-Primaquine in Plasmodium vivax Malaria
Journal article
Chu CS. et al, (2018), Clinical Infectious Diseases, 67, 1543 - 1549
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Estimating the probable cause of recurrence in Plasmodium vivax malaria: relapse, reinfection or recrudescence?
Journal article
Taylor AR. et al, (2018)
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Chloroquine Versus Dihydroartemisinin-Piperaquine With Standard High-dose Primaquine Given Either for 7 Days or 14 Days in Plasmodium vivax Malaria
Journal article
Chu CS. et al, (2019), Clinical Infectious Diseases, 68, 1311 - 1319
Recent publications
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Tafenoquine: a toxicity overview.
Journal article
Chu CS. and Hwang J., (2020), Expert Opin Drug Saf
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Vivax malaria in pregnancy and lactation: a long way to health equity
Journal article
Brummaier T. et al, (2020), Malaria Journal, 19
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Plasmodium-infected erythrocytes induce secretion of IGFBP7 to form type II rosettes and escape phagocytosis.
Journal article
Lee W-C. et al, (2020), eLife, 9
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Declining Burden of Plasmodium vivax in a Population in Northwestern Thailand from 1995 to 2016 before Comprehensive Primaquine Prescription for Radical Cure
Journal article
Chu CS. et al, (2020), The American Journal of Tropical Medicine and Hygiene, 102, 147 - 150
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Optimizing G6PD testing for Plasmodium vivax case management: why sex, counseling, and community engagement matter.
Journal article
Chu CS. et al, (2020), Wellcome open research, 5