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Malaria Overview

Billions of people live in malaria endemic countries; we aim to improve health through research that addresses this threat.

Greater participation and inclusivity, as well as recognising the value of diversity, lead to fairer opportunities to fulfil everybody's potential.

Patient-centred research is the core of our research activities, spanning 5 research units and over 50 research sites in Asia and Africa.

Paying attention to the public and communities is essential to make our programmes ethical and trustworthy, to maximise their success and impact.

Performance of the Access Bio/CareStart rapid diagnostic test for the detection of glucose-6-phosphate dehydrogenase deficiency
Posted 04/02/2020. Primaquine radical cure for treatment of Plasmodium vivax is contraindicated in patients with G6PD deficiency. Ric Price, Benedikt Ley and colleagues review evidence from 11 studies of a novel point of care diagnostic (CareStart RDT) and show overall good performance under research conditions. Further feasibility studies are under way to assess its reliability under field conditions.
Transmission dynamics and control of multidrug-resistant Klebsiella pneumoniae in neonates in a developing country
Posted 31/01/2020. Drug-resistant strains of the bacterial pathogen Klebsiella pneumoniae are an important and increasing cause of infant mortality in developing countries. In this study led by Professor Ben Cooper, researchers used mathematical modelling and whole genome sequencing to quantify the effects of antibiotics and other factors in driving the hidden transmission of this pathogen within a Cambodian neonatal unit.