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Malaria Overview

Billions of people live in malaria endemic countries; we aim to improve health through research that addresses this threat.

Greater participation and inclusivity, as well as recognising the value of diversity, lead to fairer opportunities to fulfil everybody's potential.

Patient-centred research is the core of our research activities, spanning 5 research units and over 50 research sites in Asia and Africa.

Paying attention to the public and communities is essential to make our programmes ethical and trustworthy, to maximise their success and impact.

Economic considerations support C-reactive protein testing alongside malaria rapid diagnostic tests to guide antimicrobial therapy for patients with febrile illness in settings with low malaria endemicity
Posted 17/01/2020. Malaria is no longer a common cause of febrile illness in many regions of the tropics. Yoel Lubell and colleagues consider the costs and benefits of multiplex malaria/CRP tests that are now commercially available in terms of (i) the improved health outcomes for patients with bacterial illnesses; (ii) the costs of antimicrobial resistance averted; or (iii) the economic benefits of better management of remaining malaria cases and shorter malaria elimination campaigns. They conclude that a multiplexed malaria/CRP test could be highly cost-effective and utilize the well-established funding and distribution systems already in place for malaria RDTs.
Sensitivity of C‐reactive protein for the identification of bacterial infections in northern Tanzania
Posted 07/01/2020. Identifying bacterial infections in sub-Saharan Africa is a challenge because of limited access to laboratory infrastructure. Thomas Althaus and colleagues measured high sensitivity of C-reactive protein (CRP) in detecting bacterial blood stream infections and zoonotic bacterial pathogens among febrile patients both in primary levels of care and hospitals in Moshi, northern Tanzania