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  • Completed a clinical trial on CRP-guided treatment in febrile primary care patients. This was accompanied by 5 additional publications describing other contextual factors relating to the trial (baseline antibiotic prescription in the sites; social science investigations regarding patient and healthcare worker perspectives on CRP testing)
  • In the process of rolling out a large cluster RCT of CRP testing in Vietnam
  • Produced the first of its kind menu of the costs of AMR per antibiotic drug class for LMICs and high-income settings (Antimicrob Resist Infect Control. 2018;7:98. doi: 10.1186/s13756-018- 0384-3)
  • Cost-effectiveness of interventions to improve hand hygiene in healthcare workers in middle income hospital settings (J Hosp Infect. 2018;100(2):165-75. doi: 10.1016/j.jhin.2018.05.007)
  • Completed first longitudinal study of MDR Klebsiella pneumoniae with whole genome sequencing (Front Microbiol. 2018;9:1197. doi: 10.3389/fmicb.2018.01197)
  • Proof of concept of using machine learning approach to improve antibiotic prescribing in a resource limited hospital setting (Wellcome Open Res. 2018. doi: 10.1101/367037)
  • First RCT evaluation of selective decontamination strategies in high resistance ICU settings (JAMA. 2018;320(20):2087-98. doi: 10.1001/jama.2018.13765)
  • Detailed analysis of transmission dynamics of MDR Enterobacteriaceae in a Cambodian NICU, combining genomic analysis and mathematical modelling, and the first study to quantify the effects of plasmid transfer on ward-level (bioRxiv. 2018; 436006. doi: https://doi. org/10.1101/436006)
  • Major new collaborations established with key US and European networks working on AMR (with CDC funding)
  • New grant for work on adaptive trial designs in emerging epidemics (NIHR 2018-2021)