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Thailand and SE Asia’s first Pint of Science Festival kicked Pint-of-Science1 off on Mon 15 May with a look at Killer Bugs: Disease, Detection and Destruction and an enthusiastic reception from over 50 attendees that included scientists from MORU and other institutions, business people with a background in science and students.
Pilot study detects diverse DNA in ingredients of falsified tablets
LOMWRU
10 January 2023
A recent multidisciplinary pilot study, originating from LOMWRU and the Medicine Quality Research Group of IDDO and MORU, investigated whether bacterial, plant, fungal and animal DNA in the ingredients and from the environment (eDNA) could be detected from falsified (aka counterfeit) tablets.
COPCOV investigators meet, and prepare to submit for publication
MORU Bangkok
23 December 2022
On 15-16 Dec, COPCOV investigators from around the world met in Bangkok to review study results and plan next steps. Led by co-PIs Prof Sir Nick White and Dr Will Schilling, and funded by the Wellcome Trust, the MORU-led COPCOV ( Chloroquine prevention of coronavirus disease (COVID-19) in the healthcare setting) is the world’s largest multinational trial of COVID-19 prevention.
Researchers call for antimicrobial resistance surveillance to be improved
COMRU LOMWRU MORU Bangkok
20 December 2022
The number of studies reporting antimicrobial resistance (AMR) data has increased in Africa, South and South East Asia according to new research in the International Journal of Infectious Diseases.
Are we getting tafenoquine dosing right?
MORU Bangkok SMRU
6 December 2022
Researchers analysing clinical trial data for the new antimalarial drug tafenoquine find that higher doses are needed to cure reliably vivax malaria infection.
Constant genetic surveillance necessary to keep multidrug-resistant malaria parasite strains in check, study finds
LOMWRU MORU Bangkok
1 December 2022
Continually monitoring malaria parasite populations is necessary to prevent outbreaks of previously dormant multidrug-resistant malaria strains, say University of Oxford researchers. Multidrug-resistant malaria parasite strains can rapidly grow or collapse in response to public health policy changes, say the researchers in a study published today in The Lancet.
Meta-analysis informed the updated WHO guidelines for treatment of uncomplicated malaria in the first trimester of pregnancy
SMRU
29 November 2022
A new WWARN meta-analysis, commissioned by the World Health Organization and which informed a change to its treatment guidelines, has been published in The Lancet. The study provides compelling evidence that artemether-lumefantrine should now replace quinine as the treatment of choice in the first trimester.
SMRU and BHF inaugurate new Admin Building
SMRU
29 November 2022
Today saw the long-awaited grand opening of the new Shoklo Malaria Research Unit (SMRU) / Borderland Health Foundation (BHF) Admin Building in Mae Ramat, Thailand, near the Thai-Myanmar border. And, boy was it worth the wait! Years in the planning, the very impressive new Admin Building looked absolutely stunning, the siting and architecture being universally admired by the many guests.
Bacterial infections linked to one in eight global deaths, according to GRAM study
COMRU LOMWRU MORU Bangkok
22 November 2022
Data showing 7.7 million deaths from 33 bacterial infections can guide measures to strengthen health systems, particularly in low-income settings
Combating drug-resistant malaria
MORU Bangkok
26 October 2022
MORU research has contributed to strategies to eliminate malaria in the Greater Mekong Sub-region, helping to prevent the spread of drug-resistant malaria and improving health provision and outcomes for remote communities.
Study shows clear link between antibiotic treatment and acquisition of AMR bacteria in children
COMRU SMRU
19 October 2022
A study of the genetic diversity of Streptococcus pneumoniae, the bacterium responsible for hundreds of thousands of infant deaths each year, found that deep sequencing whole pneumococcal populations gave unsurpassed sensitivity for detecting multiple colonisations and was twice as effective at detecting invasive virulent strains of the bacteria as current best methods, say researchers in a study published in Nature Microbiology.
Antimalarial chemoprophylaxis for forest goers could help accelerate malaria elimination in Cambodia
MORU Bangkok
28 September 2022
Giving people antimalarials during and after visiting the forest reduced their risk of contracting malaria 6-fold, and could be the missing piece towards eliminating malaria in Asia-Pacific and South America, say Mahidol and Oxford University researchers in a study published in The Lancet Infectious Diseases.
Call for researchers: Share your country’s national COVID-19 therapeutics guidelines
MORU Bangkok
31 August 2022
The joint MORU and IDDO Study to review global COVID-19 therapeutics guidelines, led by PIs Cintia V. Cruz, Mia Cokljat and Philippe Guérin, is examining current national COVID-19 treatment recommendations to investigate the level of variation and whether they are consistent with WHO guidelines for the pharmacological prevention and treatment of COVID-19.
Three new full Oxford Professors from MORU
Awards & Appointments MOCRU MORU Bangkok
30 August 2022
Three MORU Network staff awarded full professorship at the Nuffield Department of Medicine, University of Oxford.
INTERBIO-21st study findings could help predict infants at risk of obesity
SMRU
30 August 2022
Fetal abdomen growth and the mother’s blood fat metabolites very early in pregnancy influence a child’s weight, body fat, vision and neurodevelopment at 2 years of age
Using mathematical modelling to fight malaria
MORU Bangkok
12 August 2022
Researchers have created a mathematical model to predict genetic resistance to antimalarial drugs in Africa to manage one of the biggest threats to global malarial control.
Oxford conferences put focus on substandard and falsified antimicrobials and vaccines
Conferences & meetings
6 August 2022
MORU’s Medicine Quality Research Group (MQRG) organised a multidisciplinary hybrid meeting at Keble College, Oxford, 3-6 July for the Wellcome Collaborative Award-funded FORESFA project (‘Forensic epidemiology and impact of substandard and falsified antimicrobials on public health’).
Incomplete reporting of COVID-19 disease severity criteria compromises meta-analysis
MORU Bangkok
20 July 2022
Patients affected by COVID-19 should be treated according to the severity of their disease. However, not all key national or international organisations define severity in the same way. This imprecision in severity assessment compromises the validity of some therapeutic recommendations. Using individual patient data would better guide and improve therapeutic recommendations for COVID-19.
Field evaluation of EasyScan GO: a digital malaria microscopy device
MORU Bangkok SMRU
28 June 2022
Microscopic examination of Giemsa-stained blood films is key to quantifying and detecting malaria parasites but there can be difficulties in ensuring both a high-quality manual reading and inter-reader reliability. The EasyScan GO was developed as a potential solution to this, a microscopy device using machine-learning-based image analysis for automated parasite detection and quantification.
Enhanced vaccination against Japanese encephalitis virus could reduce encephalitis prevalence by one third in SE Asia
LOMWRU
20 June 2022
Encephalitis is a worldwide public health issue, with a substantially high burden among children in Southeast Asia. A large study of the causes of childhood encephalitis in SE Asia suggests that enhanced and effective vaccination against the Japanese encephalitis virus alone could reduce encephalitis prevalence by one third.
Congratulations Professor Sir David Warrell, appointed Knight Commander of the Order of St Michael and St George
Awards & Appointments MORU Bangkok
7 June 2022
David Warrell, our founding director, has been appointed by the Queen ‘Knight Commander of the Order of St Michael and St George for services to global Health Research and Clinical Practice’. Please join us in congratulating Sir David on receiving this richly deserved high honour!