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Largest genome-wide study of parasite provides clearest picture yet of genetic changes driving artemisinin resistance
artemisinin-genetics-resistance. Hinxton, Cambridge, UK, 19 January 2015 – The largest genome-wide association study to date of the malaria parasite Plasmodium falciparum unveils a complex genetic architecture that enables the parasite to develop resistance to our most effective antimalarial drug, artemisinin.
An updated systematic search and review of published information from over 4,000 malaria samples has identified areas in central, eastern and north-eastern India where treatment-resistant malaria parasites could be more prevalent.