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Another elimination option is to use the RTS,S malaria vaccine, which provides short term drug-independent protection against falciparum malaria. We have assessed for the first time the immunogenicity of RTS,S in Asian adults, and we also need to establish whether concomitant dihydroartemisinin-piperaquine affects it. These studies have now been completed and show good immunogenicity, no significant interactions, and they inform appropriate dosing.