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Spin and fragility are common in randomised controlled trials published in anaesthesia journals. Staying with the facts and addressing only the primary endpoint in the conclusion of clinical research reports might help reduce spin. Routinely reporting the fragility index, in turn, could deliver information about robustness, enhancing the transparency of positive dichotomous results. It is in the best interest of clinical research that authors, reviewers, and journals come together to reduce spin and address the fragility of randomised controlled trials.

Original publication




Journal article


British journal of anaesthesia

Publication Date





507 - 510


Department of Outcomes Research, Cleveland, OH, USA; Department of Intensive Care and Resuscitation, Cleveland, OH, USA; Department of Cardiothoracic Anesthesiology, Cleveland Clinic, Cleveland, OH, USA; Department of Anesthesiology and Intensive Care, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany. Electronic address:


Humans, Anesthesia, Anesthesiology, Randomized Controlled Trials as Topic, Anesthetists