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Largest genome-wide study of parasite provides clearest picture yet of genetic changes driving artemisinin resistance artemisinin-genetics-resistance. Hinxton, Cambridge, UK, 19 January 2015 – The largest genome-wide association study to date of the malaria parasite Plasmodium falciparum unveils a complex genetic architecture that enables the parasite to develop resistance to our most effective antimalarial drug, artemisinin.
Real-time genetic surveillance can support timely, evidence-based responses to shifting malaria threats
25 June 2025
A sharp decline in piperaquine-resistant strains of P. Falciparum malaria following drug policy revisions across the Greater Mekong Subregion (GMS) highlights how real-time genetic data can support timely, evidence-based responses to shifting malaria threats, say researchers in a study published in Nature Communications.
Circus arts shine spotlight on AMR in Cambodian communities
4 June 2025
In May 2025, circus performances were used to educate Cambodian youth on the correct use of antibiotics. Misuse of antibiotics is a major driver of bacterial antimicrobial resistance (AMR) worldwide. The wide availability of antibiotics over the counter in Cambodia and linguistic issues make it difficult for younger Cambodians to understand when antibiotic use is appropriate.
Landmark DeTACT project holds final Investigators’ meeting
26 May 2025
On 6-7 May in Zanzibar, Tanzania, the final investigators’ meeting of the Development of Triple Artemisinin-based Combination Therapies (DeTACT) project brought together 35 investigators from participating institutions in Bangladesh, Cambodia, Guinea, Nigeria, Niger, Tanzania, The Gambia, Rwanda, Singapore, and MORU, along with key partners from Fosun Pharma, Medicines for Malaria Venture (MMV), the WHO Global Malaria Programme, and the UK Foreign, Commonwealth and Development Office (FCDO), which funded the project over the past seven years.
UPDATE Myanmar earthquake: MAM and MOCRU provide life-saving response
23 May 2025
On 28 March 2025, a powerful earthquake (magnitude 7.8) devastated central Myanmar, with the epicentre near Mandalay, the country’s second largest city, and home to 1.5 million people. On 1 April, Medical Action Myanmar (MAM) and the Myanmar Oxford Clinical Research Unit (MOCRU) sent 70 staff to launch an emergency response.
Oxford and Thai Health Officials Sign Agreement on Infectious Disease Control
15 May 2025
On 13 May 2025, representatives from the University of Oxford and the Tak Provincial Public Health Office signed a Memorandum of Understanding to strengthen collaboration on infectious disease prevention and control along the Thai–Myanmar border. The agreement focuses on joint research into key diseases affecting the border population.
Building Better Vaccines: Dr Thitinan Kitisin Explores Tonsil Organoids Models in Thailand
23 April 2025
Years of groundwork have led Mahidol University Assistant Professor Dr Thitinan Kitisin to his first major step: leading an advanced vaccine research project in Thailand. With support from MODRA, he’s now developing one of the first tonsil organoid models in the country, a small but important step toward improving how vaccines are tested. Along the way, he’s also passing on practical research skills to the next generation of Thai scientists.
MORU-Oxford Engagement Meeting
8 April 2025
On 27 March, members of the Public and Community Engagement with Research (PCER) team at the University of Oxford met with MORU colleagues and other engagement colleagues from the University. The session focused on sharing strategies for community engagement, evaluating engagement, and exploring opportunities for future collaboration.
Blog: From post-PhD uncertainty to leading international research
4 April 2025
Dr Duong Thi Hue Kien, a Post-doc Scientist at OUCRU, has shared her experience of finishing her PhD and kickstarting her career in science. She documents the highs and the lows, as well as how she was able to move forward in her career with support from MODRA, the MORU–OUCRU Discovery Research Academy.
MORU hosts international workshop on safer drug use in obstetric and paediatric medicine through PBPK modelling
19 March 2025
Healthcare professionals, researchers, and policymakers gathered in Bangkok 12-13 March for PBPK modelling in paediatrics, pregnancy and lactation, a major international workshop addressing a longstanding issue in medicine: ensuring safer and more effective drug treatments for pregnant or lactating women and children.
Workshop seeks to strengthen pandemic preparedness in SE Asia
14 March 2025
From 18-19 Feb, SEACOVARIANTs project public engagement team members from Thailand, Viet Nam and Indonesia hosted a workshop, Southeast Asia Social, Ethical, and Engagement Aspects of Pandemic Preparedness, in Da Nang, Viet Nam.
Innovative forensics to identify origins of falsified medicines presented to UNODC and WHO
11 March 2025
On 24-26 Feb 2025, Paul Newton, Head of MORU’s Medicine Quality Research Group (MQRG), and MQRG Deputy Head Céline Caillet presented work by the MQRG at the UN Office on Drugs and Crime (UNODC) and WHO meeting, Strategic and Tactical Interventions to Address Medical Products-Related Crimes.
Bangladesh malaria mass vaccine and drug administration trial begins
19 February 2025
After more than a year of community engagement and preparation in 100 villages with 12,000 populations across the Chittagong Hill Tracts, the mass malaria vaccine (R21/Matrix M) and drug (DHA, piperaquine, and single low dose primaquine) administration study started on 15 Feb.
Identifying fake Covid-19 vaccines by analysing vial labels and vaccine liquids
31 January 2025
Researchers at MORU's Medicine Quality Research Group (MQRG), University of Oxford and collaborators, including the Serum Institute of India, have published an innovative method to identify falsified vaccines without opening the vaccine vial.
Myanmar-Thailand: Healthcare access without barriers
14 January 2025
In Myanmar, the United Nations reports that 3 million people have been displaced due to the ongoing civil war. The 2021 coup intensified conflicts and worsened the humanitarian crisis, forcing at least a hundred thousand to seek refuge and medical care in Thailand. The Tak province, a key crossing point between the two countries, sees a rising number of new migrants (with 40% of women) crossing the border every day. In response to this health emergency caused by these large-scale forced displacements, the SMRU and M-FUND projects have concentrated their efforts along the border area.
Study finds methaemoglobin levels could predict malaria recurrence
26 November 2024
A new study has found methaemoglobin levels during treatment for vivax malaria could be used to predict whether a patient would have recurrent malaria.
Dialogue drama on adolescent pregnancy in a marginalised migrant population on the Thailand-Myanmar border
20 November 2024
A participatory-action approach involving community members and adolescents resulted in a dialogue-drama on adolescent pregnancy, contraception, and choice in the event of an unplanned pregnancy. The dialogue-drama augmented discussion of traditionally taboo issues and this ethnographic method is potentially useful for similar global health settings.
MODRA Workshop 2 empowers next generation of researchers
19 November 2024
The MORU-OUCRU Discovery Research Academy (MODRA) Workshop 2 was recently held in Ho Chi Minh City, Vietnam.
The Medicine Quality Research Group invited to present at the World Health Summit, Berlin, 15th October
6 November 2024
Dr Gesa Gnegel and Dr Céline Caillet were invited to present their current work during a session at the World Health Summit. This international forum and leading global health conference brings together stakeholders from politics, science, the private sector, and civil society. The aim of this event that took place in Berlin from the 13th to the 15th of October 2024 is ‘to set the agenda for a healthier future by inspiring innovative solutions for better health and well-being for all’.
Innovative diagnostics, new tools, near-elimination strategies, cross-border collaborations top agenda at malaria elimination joint meeting
1 November 2024
From 24-26 Sept, the Asia Pacific Malaria Elimination Network (APMEN) Vivax Working Group (VxWG) and Surveillance & Response Working Group (SRWG) held their 2024 Joint Annual Meeting in Kuching, Malaysia. Co-organized by SRWG and VxWG host institutions MORU and Medicines for Malaria Venture (MMV), the event took place immediately following the 2024 International Congress for Tropical Medicine and Malaria (ICTMM).
Dr Claire Chewapreecha wins Nature Award for Inspiring Women in Science
1 November 2024
Dr Chewapreecha, a Wellcome International Intermediate Fellow and computational biologist at NDM's Mahidol-Oxford Tropical Medicine Research Unit, has been announced as the Individual Winner at this year’s Inspiring Women in Science Awards hosted by Nature and The Estée Lauder Companies. She was honoured at a ceremony in London on 31 October.