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Research Areas

Patient-centred research is the core of our research activities, spanning 5 research units and over 50 research sites in Asia and Africa.

Molecular Malaria Lab members in a semi-circle doing thumbs up.

Malaria Overview

Billions of people live in malaria endemic countries; we aim to improve health through research that addresses this threat.

Bioethics & Engagement

Paying attention to the public and communities is essential to make our programmes ethical and trustworthy, to maximise their success and impact.

Equality and Diversity group at MORU, with Lisa White, Nantasit Luangasanatip, Andrea Ruecker, Atthanee Jeeyapant, Xin Hui Chan, Marja Dondorp, Jiab, Warunee Hanpithakpong, Bencharat Thongpunchang

Equality & Diversity

Greater participation and inclusivity, as well as recognising the value of diversity, lead to fairer opportunities to fulfil everybody's potential.

Rose McGready: Malaria in pregnancy

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Research Highlights

Ambulatory induction phase treatment of cryptococcal meningitis in HIV integrated primary care clinics, Yangon, Myanmar
Posted 14/05/2021. Cryptococcal meningitis is a common serious HIV-associated infection, responsible for 15% of AIDS related deaths globally. Patients are usually treated as in-patients. Frank Smithuis and colleagues reviewed 76 patients treated with amphotericin and fluconazole as out-patients in primary care clinics in Yangon, Myanmar. One-year survival (86%) was higher than existing hospital-based treatment studies and 1029 hospitals days were saved.
Laboratory informatics capacity for effective antimicrobial resistance surveillance in resource-limited settings
Posted 11/05/2021. Microbiology laboratory data management is complex and is a rate-limiting step for AMR surveillance in low- and middle-income countries. Paul Turner, Liz Ashley, and colleagues summarise the urgent IT infrastructure requirements needed to ensure that the substantial ongoing efforts to develop capacity for AMR surveillance in LMICs realise their full potential.
Assessing the impacts of short-course multidrug-resistant tuberculosis treatment in the Southeast Asia Region using a mathematical modeling approach
Posted 07/05/2021. Multidrug-resistant tuberculosis (MDR-TB) remains a significant burden in the Southeast Asia region. Using mathematical modelling approach, Wirichada Pan-Ngum and colleagues assessed the population-level impacts of short-course MDR-TB treatment compared to the conventional therapy. Early initiation of treatment and good level of treatment eligibility are identified to be important determinants to the success of MDR-TB control programmes.

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The COPCOV Trial’s position statement on “A living WHO guideline on drugs to prevent COVID-19.”

Following WHO recommendations against the use of hydroxychloroquine in the prevention of COVID-19, including its use in controlled trials, we are reviewing the guideline and available evidence. We are concerned that this judgement from the authors of the guideline is scientifically unsound.

Read the full statement (PDF)