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Research Areas

Patient-centred research is the core of our research activities, spanning 5 research units and over 50 research sites in Asia and Africa.

Molecular Malaria Lab members in a semi-circle doing thumbs up.

Overview Malaria & Critical illness

Billions of people live in malaria endemic countries; we aim to improve health through research that addresses this threat.

Schoolchildren in the audience of a Village Drama

Bioethics & Engagement

Paying attention to the public and communities is essential to make our programmes ethical and trustworthy, to maximise their success and impact.

Equality and Diversity group at MORU, with Lisa White, Nantasit Luangasanatip, Andrea Ruecker, Atthanee Jeeyapant, Xin Hui Chan, Marja Dondorp, Jiab, Warunee Hanpithakpong, Bencharat Thongpunchang

Equality & Diversity

Greater participation and inclusivity, as well as recognising the value of diversity, lead to fairer opportunities to fulfil everybody's potential.

Rose McGready: Malaria in pregnancy

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Research Highlights

Clustering of malaria in households in the Greater Mekong Subregion: operational implications for reactive case detection
Posted 17/09/2021. One of the policies to achieve malaria elimination in the near future is reactive case detection. A secondary analysis of a large dataset of mass drug administrations in Greater Mekong Subregion found that reactive case detection in this setting is costly but results only in minimal benefits, by Lorenz Von Seidlein and colleagues
Dynamics of G6PD activity in patients receiving weekly primaquine for therapy of Plasmodium vivax malaria
Posted 15/09/2021. In Cambodian G6PD deficient variants, G6PD enzyme activity is unaffected by baseline reticulocyte counts but rises and correlates with posttreatment reticulocytosis. Qualitative G6PD tests are unlikely to misdiagnose G6PD deficient males at presentation. Too few G6PD heterozygous females preclude drawing inferences; more research is needed in this group.
A spatio-temporal analysis of scrub typhus and murine typhus in Laos; implications from changing landscapes and climate
Posted 14/09/2021. Little is known about why scrub typhus and murine typhus vary through time and space. Tamalee Roberts and colleagues investigated the impacts of climate and environment on both neglected diseases in Laos. The results suggest that global heating will increase their incidence and distribution, requiring interventions to reduce their burden.

More research highlights

Recruitment surges in COPCOV COVID-19 prevention study

As high COVID-19 daily cases and highly transmissible variants risk overwhelming countries’ healthcare systems, COPCOV, the world’s last-standing large prophylaxis RCT, faces tight timelines to determine whether chloroquine/ hydroxychloroquine prevents COVID-19

Pie Chart with COPCOV recruitment as of 7th July 2021. A black & white version of the pie chart and a table with figures can be found at https://www.tropmedres.ac/news/recruitment-surges-in-copcov-covid-19-prevention-study/copcov-recruitment-as-of-7-july-2021