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An individual patient data meta-analysis of 2,017 patients from 19 studies has found a high risk of recurrence following treatment of P. vivax malaria with artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) unless they are co-administered with primaquine. The research supports recommendations that these artemisinin-based combination therapies (ACT) should be combined with primaquine.
Emerging infections
Asia has long been the source of infectious diseases that have escalated into epidemics or pandemics, notably SARS-CoV-2 and influenza. As new pandemic threats continue to arise, research at MORU focuses on genomic and immunological surveillance of emerging infections, the development and evaluation of new methods of assessing therapeutics, and their large-scale assessment in order to inform policies and practices.