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The Shoklo Malaria Research Unit (SMRU) led Malaria Elimination Task Force has undertaken mass drug administration campaigns in Eastern Karen State, Myanmar in areas with a high sub microscopic Plasmodium falciparum parasite prevalence.
Ensitrelvir shows strong antiviral activity against COVID-19 in first head-to-head comparison with Paxlovid
28 October 2025
The oral antiviral ensitrelvir is a highly effective treatment for COVID-19, showing potent in-vivo antiviral activity comparable to ritonavir-boosted nirmatrelvir (Paxlovid), say MORU, Mahidol and University of Oxford researchers in a major international study published in The Lancet Infectious Diseases.
Antimalarial resistance deserves higher priority in global AMR strategy
15 October 2025
In a new commentary for BMJ Global Health, University of Oxford researchers argue that antimicrobial resistance (AMR) interventions often ignore morally relevant differences between microbes. They highlight that antimalarial resistance disproportionately affects low- and middle-income countries, particularly children in sub-Saharan Africa, and deserves greater attention in global health research and intervention priorities. The team calls for more equitable resource allocation, policy change, and advocacy to ensure AMR responses are just and inclusive.
FD-TACT malaria treatment trial launches patient recruitment in Rwanda
8 October 2025
A Phase 3 pivotal trial, led by MORU and funded by Japan’s Global Health Innovative Technology Fund (GHIT), has begun to evaluate a novel fixed-dose triple artemisinin-based combination treatment (FD-TACT) for uncomplicated Plasmodium falciparum malaria.
MORU Community Advisory Boards meet in Bangkok
26 September 2025
From 21-22 Aug, twenty five MORU Major International Programme (MIP) colleagues attended the second CAB-NET meeting in Bangkok and online. Run by MORU Bioethics & Engagement (B&E), CAB-NET is a network that bring together the facilitators of community advisory boards (CABs) run by the MORU MIP to share activity updates, ideas and best practices, training, and network.
Joel Tarning awarded RSTMH’s 2025 Chalmers Medal
25 September 2025
Professor Joel Tarning, head of MORU’s Clinical Pharmacology Department, has been honoured with the award of the Royal Society of Tropical Medicine and Hygiene’s Chalmers Medal for his exceptional contribution to the field of clinical pharmacology of neglected tropical diseases, and in particular antimalarial therapy.
A migrant mother’s 4-hr walk for antenatal care
24 September 2025
On the Thai-Myanmar border, life is often a daily struggle, especially for expectant mothers like migrant day labourer Daw Mu (name changed for privacy), who lives in a village near Jaydi Koh in Tak Province’s Phop Phra District. Now three months pregnant with her second child, Daw Mu must walk 4 hours to the Jaydi Koh SMRU/BHF outreach clinic for antenatal care, often with her four-year-old son by her side.
SMRU honored at One Health Conference
19 August 2025
On 13 August 2025, SMRU received the “One Health Champion” First Prize for its response to a cholera outbreak along the Thai–Myanmar border. Awarded at a national One Health conference, the recognition highlights SMRU’s excellence in cross-border disease surveillance and public health response through collaborative, sustainable policy efforts.
Simple new method that measures viral clearance means antibody treatments for COVID and ‘flu can be quickly assessed for effectiveness, say MORU researchers
7 August 2025
Measuring the rate of viral clearance from the back of the mouth in patients with mild infections can be used to determine quickly and inexpensively if an antibody is effective in future COVID-19, influenza and other respiratory virus pandemics, say researchers in a letter published today in The Lancet.
Two nights of talks for Pint of Science Laos 2025
16 July 2025
In May 2025, LOMWRU organised the 4th Pint of Science event in Vientiane, Laos, as part of the global Pint of Science festival. The successful event, open to the general public, had local researchers from public health, wildlife conservation, and geology giving fun and interesting talks over two nights, giving insights into how their work impacts Laos.
15 emerging Asian global health researchers selected to join MODRA
11 July 2025
The MORU – OUCRU Discovery Research Academy (MODRA) announces its 2025 cohort of emerging researchers in global health and infectious diseases.
Real-time genetic surveillance can support timely, evidence-based responses to shifting malaria threats
25 June 2025
A sharp decline in piperaquine-resistant strains of P. Falciparum malaria following drug policy revisions across the Greater Mekong Subregion (GMS) highlights how real-time genetic data can support timely, evidence-based responses to shifting malaria threats, say researchers in a study published in Nature Communications.
Circus arts shine spotlight on AMR in Cambodian communities
4 June 2025
In May 2025, circus performances were used to educate Cambodian youth on the correct use of antibiotics. Misuse of antibiotics is a major driver of bacterial antimicrobial resistance (AMR) worldwide. The wide availability of antibiotics over the counter in Cambodia and linguistic issues make it difficult for younger Cambodians to understand when antibiotic use is appropriate.
Landmark DeTACT project holds final Investigators’ meeting
26 May 2025
On 6-7 May in Zanzibar, Tanzania, the final investigators’ meeting of the Development of Triple Artemisinin-based Combination Therapies (DeTACT) project brought together 35 investigators from participating institutions in Bangladesh, Cambodia, Guinea, Nigeria, Niger, Tanzania, The Gambia, Rwanda, Singapore, and MORU, along with key partners from Fosun Pharma, Medicines for Malaria Venture (MMV), the WHO Global Malaria Programme, and the UK Foreign, Commonwealth and Development Office (FCDO), which funded the project over the past seven years.
UPDATE Myanmar earthquake: MAM and MOCRU provide life-saving response
23 May 2025
On 28 March 2025, a powerful earthquake (magnitude 7.8) devastated central Myanmar, with the epicentre near Mandalay, the country’s second largest city, and home to 1.5 million people. On 1 April, Medical Action Myanmar (MAM) and the Myanmar Oxford Clinical Research Unit (MOCRU) sent 70 staff to launch an emergency response.
Oxford and Thai Health Officials Sign Agreement on Infectious Disease Control
15 May 2025
On 13 May 2025, representatives from the University of Oxford and the Tak Provincial Public Health Office signed a Memorandum of Understanding to strengthen collaboration on infectious disease prevention and control along the Thai–Myanmar border. The agreement focuses on joint research into key diseases affecting the border population.
Building Better Vaccines: Dr Thitinan Kitisin Explores Tonsil Organoids Models in Thailand
23 April 2025
Years of groundwork have led Mahidol University Assistant Professor Dr Thitinan Kitisin to his first major step: leading an advanced vaccine research project in Thailand. With support from MODRA, he’s now developing one of the first tonsil organoid models in the country, a small but important step toward improving how vaccines are tested. Along the way, he’s also passing on practical research skills to the next generation of Thai scientists.
MORU-Oxford Engagement Meeting
8 April 2025
On 27 March, members of the Public and Community Engagement with Research (PCER) team at the University of Oxford met with MORU colleagues and other engagement colleagues from the University. The session focused on sharing strategies for community engagement, evaluating engagement, and exploring opportunities for future collaboration.
Blog: From post-PhD uncertainty to leading international research
4 April 2025
Dr Duong Thi Hue Kien, a Post-doc Scientist at OUCRU, has shared her experience of finishing her PhD and kickstarting her career in science. She documents the highs and the lows, as well as how she was able to move forward in her career with support from MODRA, the MORU–OUCRU Discovery Research Academy.
MORU hosts international workshop on safer drug use in obstetric and paediatric medicine through PBPK modelling
19 March 2025
Healthcare professionals, researchers, and policymakers gathered in Bangkok 12-13 March for PBPK modelling in paediatrics, pregnancy and lactation, a major international workshop addressing a longstanding issue in medicine: ensuring safer and more effective drug treatments for pregnant or lactating women and children.
Workshop seeks to strengthen pandemic preparedness in SE Asia
14 March 2025
From 18-19 Feb, SEACOVARIANTs project public engagement team members from Thailand, Viet Nam and Indonesia hosted a workshop, Southeast Asia Social, Ethical, and Engagement Aspects of Pandemic Preparedness, in Da Nang, Viet Nam.