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Hydroxychloroquine could still prevent COVID-19 and save tens of thousands of lives around the world, say leading scientific researchers. While it doesn’t work in treatment of hospitalised patients, it could still prevent infections. However, fraudulent data, unjustified extrapolation and exaggerated safety concerns together with intense politicisation and negative publicity may stop COPCOV, the only large, global clinical trial testing hydroxychloroquine in COVID-19 prevention, from ever finding out.

Person using mobile app and screenshot of app interface © MORU 2020. Photographer: Supa-at (Ice) Asarath.
COPCOV participants will use a mobile app to report their health daily.

Ensuring vaccine cold chain integrity: A rapid and low-cost test for identifying heat-exposed sucrose-containing vaccines

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Arman BY. et al, (2026), International Journal of Pharmaceutics: X, 11, 100467 - 100467

Rickettsial seropositivity in Lao PDR smallholder livestock farms: Implications for animal and human health.

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Tawfik C. et al, (2026), One health (Amsterdam, Netherlands), 22

Reconsidering the clinical assessment of resistance to slowly eliminated antimalarial drugs in high-transmission settings

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White NJ. and Watson JA., (2026), The Lancet Infectious Diseases, 26, e240 - e247

Burden of diarrhoeal diseases among hospitalised patients in Thailand: a retrospective national database analysis (2014-2022).

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Srisaeng S. et al, (2026), The Lancet regional health. Southeast Asia, 48

Comparison of CD4 T-Cell Response in Plasmodium falciparum and vivax Malaria

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Nalubega M. et al, (2026), The Journal of Infectious Diseases, 233, e891 - e901

Research briefs as tools for dialogue: Practitioner insights on a realist review of community engagement

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van der Westhuizen H-M. et al, (2026), Wellcome Open Research, 11, 229 - 229

Population pharmacokinetics of DNDI-6148 in healthy adults

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Assmus F. et al, (2026), PLOS Neglected Tropical Diseases, 20, e0014220 - e0014220

Impact of switching from manual to automated aerobic blood culture on bacteremia diagnosis in Lao PDR

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Jaksuwan R. et al, (2026), Microbiology Spectrum, 14

G6PD deficiency in Indonesia: a systematic review and update of prevalence and variant maps in the context of malaria elimination

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Sadhewa A. et al, (2026), The Lancet Regional Health - Western Pacific, 69, 101840 - 101840

Core outcome measurement set for clinical trials in dengue: an international Delphi consensus study (DEN-CORE)

Journal article

Yacoub S. et al, (2026), The Lancet Infectious Diseases, 26, e231 - e244

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