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No one knows exactly why resistance to malaria drugs always emerges first in this remote western province of Cambodia, nestled in the Cardamom Mountains. “The reasons are as much social as biological,” says malariologist Tom Peto, who is here in this dusty, unremarkable-looking town battling the latest threat to global malaria control: multiple drug–resistant (MDR) malaria.
Emerging infections
Asia has long been the source of infectious diseases that have escalated into epidemics or pandemics, notably SARS-CoV-2 and influenza. As new pandemic threats continue to arise, research at MORU focuses on genomic and immunological surveillance of emerging infections, the development and evaluation of new methods of assessing therapeutics, and their large-scale assessment in order to inform policies and practices.