Antibodies from Patients with Melioidosis Recognize Burkholderia mallei but Not Burkholderia thailandensis Antigens in the Indirect Hemagglutination Assay
Tiyawisutsri R., Peacock SJ., Langa S., Limmathurotsakul D., Cheng AC., Chierakul W., Chaowagul W., Day NPJ., Wuthiekanun V.
ABSTRACT The indirect hemagglutination assay routinely used to detect antibodies to Burkholderia pseudomallei was modified to detect cross-reactivity of antibodies to B. pseudomallei , B. mallei , and B. thailandensis antigens. We demonstrate a lack of cross-reactivity between B. pseudomallei and B. thailandensis but marked cross-reactivity between B. pseudomallei and B. mallei .