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ABSTRACT Polymorphisms in exon 1 of the MBL-2 gene, resulting in reduced plasma levels of mannose binding lectin, were significantly overrepresented in 23 patients with primary antibody deficiency and culture-proven mycoplasma infections ( P = 0.0038). This association persisted with the inclusion of a further nine suspected (doxycycline-responsive) cases ( P = 0.0087). The lectin was shown to bind to three strains of mycoplasma.

Original publication

DOI

10.1128/iai.73.8.5238-5240.2005

Type

Journal article

Journal

Infection and Immunity

Publisher

American Society for Microbiology

Publication Date

08/2005

Volume

73

Pages

5238 - 5240