A Randomized Controlled Trial of Three- versus Five-Day Artemether-Lumefantrine Regimens for Treatment of Uncomplicated Plasmodium falciparum Malaria in Pregnancy in Africa

Onyamboko MA., Hoglund RM., Lee SJ., Kabedi C., Kayembe D., Badjanga BB., Turner GDH., Jackson NV., Tarning J., McGready R., Nosten F., White NJ., Day NPJ., Fanello C.

Artemether-lumefantrine antimalarial efficacy in pregnancy could be compromised by reduced drug exposure. Population-based simulations suggested that therapeutic efficacy would be improved if the treatment duration was increased.

DOI

10.1128/aac.01140-19

Type

Journal article

Journal

Antimicrobial Agents and Chemotherapy

Publisher

American Society for Microbiology

Publication Date

21/02/2020

Volume

64

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