Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.
Skip to main content

<ns4:p><ns4:bold>Background</ns4:bold><ns4:bold>:</ns4:bold> Natural <ns4:italic>Wolbachia </ns4:italic>infections in malaria mosquitoes were recently reported in Africa, and negatively correlated with the development of <ns4:italic>Plasmodium falciparum</ns4:italic> in the vectors. The occurrence and effects of <ns4:italic>Wolbachia </ns4:italic>infections outside Africa have not been described and may have been underestimated.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold><ns4:bold>:</ns4:bold> Mosquitoes were collected by human-landing catch during May and June 2017 in ten villages in Kayin state, Myanmar. Closely related species of malaria vectors were identified with molecular assays. <ns4:italic>Wolbachia</ns4:italic> infection rates were assessed with quantitative real-time PCR.</ns4:p><ns4:p> <ns4:bold>Results:</ns4:bold> Low titer of <ns4:italic>Wolbachia </ns4:italic>DNA was detected in 13/370 samples in six malaria vector species. Phylogenetic analysis based on 16S rRNA sequences revealed a high diversity of <ns4:italic>Wolbachia </ns4:italic>strains and identified lineages different from those described in the African malaria mosquitoes.</ns4:p><ns4:p> <ns4:bold>Conclusion:</ns4:bold> These low-density genetically diverse natural <ns4:italic>Wolbachia </ns4:italic>infections question the ecology and biology of <ns4:italic>Wolbachia</ns4:italic>-<ns4:italic>Anopheles</ns4:italic> interactions<ns4:italic> </ns4:italic>in Southeast Asia. Their effects on malaria transmission and mosquito vectors are yet to be determined.</ns4:p>

Original publication

DOI

10.12688/wellcomeopenres.15005.3

Type

Journal article

Journal

Wellcome Open Research

Publisher

F1000 Research Ltd

Publication Date

23/09/2019

Volume

4

Pages

11 - 11