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We report here a case of hepatic lymphoma and splenic aspergillosis in an elderly patient with diabetes mellitus, exhibiting hepatosplenic abscesses mimicking melioidosis. Immunohistochemistry confirmed the diagnosis of a diffuse hepatic large B-cell lymphoma. Biopsy of the spleen revealed a clump of fungus with a slender shape and dichotomous branching, morphologically consistent with aspergillosis. Hepatosplenic abscesses are a common presentation in melioidosis, but this case reveals this assumption can lead to misdiagnosis. Histological and microbiological confirmation are required, especially in patients with hepatosplenic lesions.

Type

Journal article

Journal

The Southeast Asian journal of tropical medicine and public health

Publication Date

03/2016

Volume

47

Pages

223 - 226

Keywords

Humans, Melioidosis, Abscess, Aspergillosis, Liver Neoplasms, Liver Diseases, Splenic Diseases, Diagnosis, Differential, Immunohistochemistry, Fatal Outcome, Aged, Thailand, Male, Lymphoma, Large B-Cell, Diffuse