Host Biomarkers Reflect Prognosis in Patients Presenting With Moderate Coronavirus Disease 2019: A Prospective Cohort Study.

Chandna A., Mahajan R., Gautam P., Mwandigha L., PRIORITISE Study Investigators None., Kumar P., Varghese GM., Koshiaris C., Lubell Y., Burza S.

Efficient resource allocation is essential for effective pandemic response. We measured host biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found that different biomarkers predict distinct clinical outcomes. Interleukin (IL)-1ra, IL-6, IL-10, and IL-8 exhibit dose-response relationships with subsequent disease progression and could potentially be useful for multiple use-cases.

DOI

10.1093/ofid/ofac526

Type

Journal article

Journal

Open forum infectious diseases

Publication Date

10/2022

Volume

9

Addresses

Cambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.

Keywords

PRIORITISE Study Investigators

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