{ "items": [ "\n\n
\n \n 6 March 2019\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nLorenz Von Seidlein tells SciDev.Net that mass drug administration as \u201cpresumptive treatment\u201d to clear the parasite reservoir was carried out in eight villages spread across Cambodia, Lao PDR, Myanmar and Vietnam. By the third month, the prevalence of P. falciparum had decreased by 92 % in those villages. Over the subsequent nine months, P. falciparum infections returned but stayed well below baseline levels, showing that MDA can stop transmission of falciparum malaria and reduce its prevalence in SE Asia, where resistance to artemisinin has hampered elimination efforts.
\n \n\n\n \n 1 March 2019\n \n
\n\n \n\n \n\n \n \n \n \n KIMORU\n \n \n\n \n\n\n
\n \n\n \n \n \nWorking closely with the University of British Columbia (UBC)'s Support Program to Advance Research Capacity (SPARC), MORU Malaria Researcher Dr Katherine Plewes was recently awarded a 3-year, C$971,551 grant for her study on Evaluating the renoprotective effect of acetaminophen in pediatric severe falciparum malaria: A randomized controlled trial.
\n \n\n\n \n 26 February 2019\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nOn 12 Feb 2019, Professor Arjen Dondorp published a new book: Sepsis Management in Resource-limited Settings. The result of a 3-year project led by MORU and the European Society of Intensive Care Medicine (ESICM), the book was written by critical care physicians from around the globe.
\n \n\n\n \n 12 February 2019\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nOn 24-25 Jan 2019, investigators met in Bangkok to launch the Developing Triple Artemisinin-based Combination Therapies (DeTACT) Project. Led by MORU and funded by UKaid and the UK Department for International Development (DfID), DeTACT is a large, 14 site trial in 8 African and 5 Asian countries that will study the efficacy, safety and tolerability of two Triple Artemisinin Combination Therapy (TACT) combinations, using combinations of existing antimalarial drugs.
\n \n\n\n \n 18 January 2019\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nA recent WWARN individual patient meta-analysis has gathered 18 published and unpublished studies from Africa and Asia to explore the relationships between identified Kelch 13 mutant alleles and delayed parasite clearance. The study results show one P. falciparum specific mutant and 20 pfk13 propeller region mutant alleles are strongly associated with the slow clearance phenotype, including 15 mutations that have not been confirmed before. It was reassuring that no pfk13 alleles associated with slow parasite clearance were observed in the parasites from African studies gathered between 2000-2017.
\n \n\n\n \n 16 January 2019\n \n
\n\n \n\n \n\n \n \n \n \n COMRU\n \n \n \n \n General\n \n \n\n \n\n\n
\n \n\n \n \n \nMalaria causes nearly half a million deaths worldwide every year. Ninety percent of them are in sub-Saharan Africa, where poor infrastructure limits delivery of drugs. But now there is worry that those drugs are losing effectiveness as disease strains become resistant. PBS News Hour special correspondent Fred de Sam Lazaro reports from Cambodia, where scientists are researching and tracking new outbreaks.
\n \n\n\n \n 16 January 2019\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nDoctors in Northern Cambodia are trialling a new drug combination therapy in a bid to stop the spread of drug resistant strains of malaria.
\n \n\n\n \n 18 December 2018\n \n
\n\n \n\n \n\n \n \n \n \n General\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nAn inspiring doctor and scientist of great compassion and intellect, Sir David Weatherall died 8 Dec 2018. A Nuffield Professor of Medicine, founder of the MRC Weatherall Institute of Molecular Medicine and a member of Wellcome\u2019s Board throughout the 1990s, Sir David was instrumental in the creation of MORU back in 1979.
\n \n\n\n \n 18 December 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nA new Piperaquine Pharmacokinetics in Pregnancy Study Group is now open for participation at WWARN. The analysis hopes to determine the effect of pregnancy on the pharmacokinetic (PK) properties of piperaquine and contribute evidence to inform decisions on the use and optimal dosing of piperaquine in pregnant women.
\n \n\n\n \n 12 December 2018\n \n
\n\n \n\n \n\n \n \n \n \n General\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nThis article, written by Professor Nick Day at MORU and published in the November 2018 issue of the Oxford Alumni Newsletter, describes in a nutshell all the good work our Centre is doing to promote Global Oxford.
\n \n\n\n \n 21 November 2018\n \n
\n\n \n\n \n\n \n \n \n \n Conferences & meetings\n \n \n \n \n LOMWRU\n \n \n\n \n\n\n
\n \n\n \n \n \nOver 200 delegates travelled from more than 50 countries to attend the first ever conference on Medicine Quality and Public Health (MQPH 2018) in Oxford from 23-28 Sept. The conference, at Keble College, brought together experts in pharmacy, public health, chemistry, law, sociology, governance and ethics, from medicines regulatory authorities, academia, pharmaceutical industry, NGOs, and international organisations.
\n \n\n\n \n 20 November 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nProgress against malaria has stalled, and the disease remains a significant threat to billions of people despite the expensive, decades-long efforts to contain it. In an encouraging development, MORU reported complete success in curing hundreds of patients in Southeast Asia with new three-drug combinations mixing fast-acting artemisinin with two longer-lasting drugs. It it hoped that triple therapy should become the standard for malaria treatment.
\n \n\n\n \n 16 November 2018\n \n
\n\n \n\n \n\n \n \n \n \n Conferences & meetings\n \n \n \n \n MORU Bangkok\n \n \n \n \n Public Engagement\n \n \n\n \n\n\n
\n \n\n \n \n \nVisit the Radcliffe Science Library before 4th January 2019 to see a new art exhibition of 14 prints illustrating the global health impact of poor quality medicines. The proliferation of poor quality medicines is an important but neglected public health problem, threatening millions of people all over the world, both in developing and wealthy countries.
\n \n\n\n \n 9 November 2018\n \n
\n\n \n\n \n\n \n \n \n \n Awards & Appointments\n \n \n \n \n General\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nOxford University has been ranked as the world's best institution for medical and health teaching and research in the Times Higher Education World University Rankings for the eighth consecutive year. This ranking is based on criteria measuring teaching, research, industry income, international outlook and citations. It was noted that both research and clinical trials are supported by our network of international research units in Africa and Asia.
\n \n\n\n \n 9 November 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nA systematic review analyses the results of 177 trials conducted between 1982 and 2016, including 18,436 patients who underwent electrocardiographic evaluation during malaria clinical trials. Nick White and colleagues found that serious cardiovascular side effects, which include sudden cardiac death, are very rare in the treatment of malaria with quinoline antimalarials. The work emphasises the importance of continued pharmacovigilance with the increasing use of quinoline antimalarials in mass treatment strategies such as intermittent preventative treatment and mass drug administration.
\n \n\n\n \n 7 November 2018\n \n
\n\n \n\n \n\n \n \n \n \n MOCRU\n \n \n\n \n\n\n
\n \n\n \n \n \nThe incidence of malaria has continued to drop dramatically in remote rural villages in Myanmar after community workers trained only to detect and treat malaria began providing basic health care as well as malaria services, researchers affiliated with MOCRU, our Myanmar-Oxford Clinical Research Unit, have said.
\n \n\n\n \n 7 November 2018\n \n
\n\n \n\n \n\n \n \n \n \n Conferences & meetings\n \n \n \n \n LOMWRU\n \n \n\n \n\n\n
\n \n\n \n \n \nThe manufacture and distribution of medicines is a global industry, tainted by fake and substandard products. Not only might these drugs not work as expected, but some are even contributing to antimicrobial resistance. So, what\u2019s in your medicine cabinet? This is an article on Mosaic, a Wellcome publication
\n \n\n\n \n 7 November 2018\n \n
\n\n \n\n \n\n \n \n \n \n Conferences & meetings\n \n \n \n \n LOMWRU\n \n \n\n \n\n\n
\n \n\n \n \n \nEvery person has the right to expect that when they use a medical product, whether medicine, vaccine or diagnostic kit, it works. But too often, that is not the case. Substandard medical products result from errors, negligence or poor practice in manufacturing, transportation and/or storage. In contrast, falsified products result from criminal fraud. Both innovative and generic products are affected.
\n \n\n\n \n 29 October 2018\n \n
\n\n \n\n \n\n \n \n \n \n Conferences & meetings\n \n \n \n \n LOMWRU\n \n \n\n \n\n\n
\n \n\n \n \n \nOver 200 delegates traveled from more than 50 countries to attend the first ever conference on Medicine Quality and Public Health (MQPH) in Oxford from 23-28 September 2018. The conference brought together experts from academia, public health, pharmacy, chemistry, law, ethics, social sciences, public engagement, health policy, with national medicines regulatory authorities, NGOs, international organizations and donors. Conference partners presented the latest evidence on substandard, falsified and unregulated medicines, and discussed strategies to tackle this global challenge.
\n \n\n\n \n 27 October 2018\n \n
\n\n \n\n \n\n \n \n \n \n Awards & Appointments\n \n \n \n \n LOMWRU\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nCTMGH have been nominated for the Market Research Society President's Medal, awarded annually to an organisation that conduct extraordinary research but who might not be recognised through the usual channels. Our Centre is noted for its ingenious use of freely available online satellite images to gath data on the use of antibiotics in unmapped and inaccessible villages in rural Thailand and Laos. Researchers use the images to identify representative clusters of potential participants.
\n \n\n\n \n 24 October 2018\n \n
\n\n \n\n \n\n \n \n \n \n MOCRU\n \n \n\n \n\n\n
\n \n\n \n \n \nThe incidence of malaria cases continued to drop dramatically in rural and remote Myanmar villages after community workers trained only to detect and treat malaria began providing basic health care as well as malaria services. Adding the health services to malaria control benefitted the villagers access to health and improved malaria services \u2013 paving the way for malaria elimination.
\n \n\n\n \n 24 October 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n \n \n Public Engagement\n \n \n\n \n\n\n
\n \n\n \n \n \nCome and meet us at the ASTMH conference, to enjoy science over a pint and bite to eat: Outbreaks, from Ebola to Zika on Mon 29th Oct. Mosquitoes, the most dangerous animals in the world on Tue 30th. Global health terror night: bats, mites and other creepy crawlies on Wed 31st. We will be at The Vintage, 3121 Magazine St, New Orleans, 7-9pm
\n \n\n\n \n 4 October 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nOn 4 Oct 2018, the MORU Malaria Dept, in collaboration with the Global Sepsis Alliance (GSA), hosted the inaugural meeting of a proposed Asian Sepsis Alliance in Bangkok.
\n \n\n\n \n 28 September 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nIn this Science blog, field researchers, Dr Giacomo Zanello, Dr Marco Haenssgen, Ms Nutcha Charoenboon and Mr Jeffrey Lienert explain the importance of continuing to improve survey research techniques when working in rural areas of developing countries.
\n \n\n\n \n 26 September 2018\n \n
\n\n \n\n \n\n \n \n \n \n Awards & Appointments\n \n \n \n \n General\n \n \n\n \n\n\n
\n \n\n \n \n \nOxford University is rated world\u2019s number one for the third straight year in the Times Higher Education world university rankings. Oxford, the only UK University ever to top the international rankings, keeps first spot through the outstanding quality of its research, teaching and innovation.
\n \n\n\n \n 12 September 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nMORU is participating in a project to reduce antibiotic resistance on farms in Asia by educating farmers. In his first 12 years working as a vet in Bangladesh, Bikash Chandra Saha routinely prescribed antibiotics. Then he learned of the devastating impact of antimicrobial resistance on human health - and it revolutionized his treatment choices.
\n \n\n\n \n 12 September 2018\n \n
\n\n \n\n \n\n \n \n \n \n MOCRU\n \n \n\n \n\n\n
\n \n\n \n \n \nDr Myo Maung Maung Swe and Htet Htet Aung from our MOCRU unit in Myanmar were awarded grants by the International Society for Infectious Diseases and Wellcome. Myo Maung will study antibiotics use and antimicrobial resistance public awareness in Myanmar; Htet Htet will conduct a study on Ethical challenges when offering pregnant women with Hepatitis B short course treatment to prevent transmission.
\n \n\n\n \n 4 September 2018\n \n
\n\n \n\n \n\n \n \n \n \n Conferences & meetings\n \n \n \n \n LOMWRU\n \n \n\n \n\n\n
\n \n\n \n \n \nA pioneering academic conference will bring together, for the first time, people from all over the world dealing with the problem of poor quality medicines and their impact on public health. The Medicine Quality & Public Health conference will take place at Keble College, Oxford, 23-28 Sept 2018. It will provide a unique opportunity for health authorities, scientists, pharmacists, lawyers and international organisations to discuss the problem and outline the necessary steps to tackle the issue on a global scale.
\n \n\n\n \n 4 September 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nA team of researchers led by Yoel Lubell at MORU and IDDO used data from the USA and Thailand to link the consumption of antibiotics with the direct and indirect costs of treating patients for five drug-resistant bacterial infections.
\n \n\n\n \n 22 August 2018\n \n
\n\n \n\n \n\n \n \n \n \n Awards & Appointments\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nThe University of Oxford's Medical Sciences Divisional Panel has conferred the title of Associate Professor on three members of our academic staff: Rogier van Doorn (OUCRU), Lorenz von Seidlein (MORU) and George Warimwe (KWTRP). This title is awarded in recognition of their distinction in their respective fields and contributions to the research and teaching, and we congratulate them on their success.
\n \n\n\n \n 26 July 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n \n \n SMRU\n \n \n\n \n\n\n
\n \n\n \n \n \nScientists are racing to stamp out the disease in Southeast Asia before unstoppable strains spread. This article features MORU, SMRU and colleagues, and explains what is happening and what we are doing to eliminate drug-resistant malaria in Southeast Asia before it spreads
\n \n\n\n \n 19 June 2018\n \n
\n\n \n\n \n\n \n \n \n \n Awards & Appointments\n \n \n \n \n SMRU\n \n \n\n \n\n\n
\n \n\n \n \n \nASTMH nominated Professor Rose McGready, SMRU Deputy Director, as an Honorary International Fellow. Rose received the prestigious award in recognition of outstanding accomplishment by an \u201cindividual not an American citizen who has made eminent contributions to some phase of tropical medicine and hygiene\u201d. Rose will formally receive her award at the ASTMH Annual Meeting, to be help 28 Oct-1 Nov in New Orleans, Louisiana.
\n \n\n\n \n 15 June 2018\n \n
\n\n \n\n \n\n \n \n \n \n Conferences & meetings\n \n \n \n \n LOMWRU\n \n \n\n \n\n\n
\n \n\n \n \n \nThe proliferation of poor quality medical products is an important but neglected public health problem, threatening millions of people all over the world, both in developing and wealthy countries. A pioneering conference will bring leading professionals from all over the world to Oxford, September 23-28, to discuss strategies for tackling poor quality medical products on a global scale.
\n \n\n\n \n 13 June 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nCurrent recommended treatment regimens for the most widely used medicine for uncomplicated Plasmodium falciparum malaria may be sub-optimal for small children and pregnant women according to a study led by Professor Joel Tarning.
\n \n\n\n \n 8 June 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nOne of the world\u2019s most widely used anti-malarial drugs is safe to use, say researchers, after a thorough review and analysis of nearly 200,000 malaria patients who\u2019d taken the drug dihydroartemisinin-piperaquine (DHA-PPQ). There is such a low risk of sudden unexpected death from DHA-PPQ, one of the world\u2019s most effective medicines to treat malaria, that there is no need to limit its current use.
\n \n\n\n \n 30 May 2018\n \n
\n\n \n\n \n\n \n \n \n \n Conferences & meetings\n \n \n \n \n LOMWRU\n \n \n\n \n\n\n
\n \n\n \n \n \nIn this Science Blog published on Oxford University website, Prof Paul Newton, Head of the Medicine Quality Group at the Infectious Diseases Data Observatory (IDDO) and the MORU Tropical Health Network and NDM Professor of Tropical Medicine i, explains the need for new strategies for tackling poor quality medical products.
\n \n\n\n \n 25 May 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nPrimaquine can be used to prevent the transmission of falciparum malaria from human to mosquito. Bob Taylor and colleagues at the Mahidol Oxford Research Unit (MORU) have developed an age-based regimen for single low-dose primaquine to block the transmission of malaria in sub-Saharan Africa.
\n \n\n\n \n 23 May 2018\n \n
\n\n \n\n \n\n \n \n \n \n Conferences & meetings\n \n \n \n \n LOMWRU\n \n \n\n \n\n\n
\n \n\n \n \n \nThe first-ever dedicated academic conference to discuss Medicine Quality & Public Health bringing together people from a diversity of sectors: public health, national regulatory authority, pharmacy, biomedical, chemistry, law, ethics, cultural and social sciences, the pharmaceutical industry, international organisations, NGOs, national procurement centres, also scientists working on internet and pharmaceutical forensics. 23rd-28th September 2018 at Keble College, Oxford. Submit your abstract by 1 June 2018
\n \n\n\n \n 22 May 2018\n \n
\n\n \n\n \n\n \n \n \n \n Awards & Appointments\n \n \n \n \n SMRU\n \n \n\n \n\n\n
\n \n\n \n \n \nOn 10 May 2018, SMRU Deputy Director Rose McGready was awarded the Alumni Award for Service to Humanity by the University of Sydney. The Alumni Award recognizes the personal contribution of alumni who, through service to philanthropy, improve the lives of those in need. It also seeks to recognize the significant involvement of Sydney alumni in projects that enrich local or international communities.
\n \n\n\n \n 11 May 2018\n \n
\n\n \n\n \n\n \n \n \n \n MORU Bangkok\n \n \n\n \n\n\n
\n \n\n \n \n \nDr Marco J Haenssgen discusses the application of management thinking to solving the growing global problem of antimicrobial resistance.
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