Being based at a tropical medicine research unit serving South East Asia drives our group to be closely integrated with the other disciplines. Our modelling work is therefore highly pragmatic and data driven often involving dynamic interplay with experiment and field research. Our research focus is mathematical models for the transmission, control and elimination of drug sensitive and resistant malaria in South East Asia. We also use mathematics in areas as diverse as: predicting gestational age given fundal height; the potential impact of collecting epidemiological information on fever in resource poor settings; the effect of multivalent vaccines on the serotype distribution of streptococcus pneumoniae; characterizing the natural history of infection for re-infecting, antigenically diverse pathogens and Markov model for cost-effectiveness analysis of Mass Screening And Treatment (MSAT) against rapid tests.