Mathematical and Economic Modelling
The MAEMOD team try a new approach to modelling
- Over 100 publications since the last core renewal consisting of primary research, reviews and invited commentaries, many of which are in high impact journals.
- Modelling artemisinin resistant malaria using both in-host and transmission models.
- Multiple modelling projects to support malaria elimination, including the use of spatially explicit models based on near real time data from malaria control programmes. Contributed to the design of a Medicins Sans Frontiers malaria elimination trial now underway in Cambodia.
- Worked with WWARN to develop standardized methods of interpreting the malaria parasite clearance curve.
- Transmission modelling of leptospirosis, nosocomial Gram+ve and Gram-ve infections and influenza in a variety of settings.
- Completed an evaluation of pandemic influenza plans and association with pandemic influenza outcomes.
- Developed a modelling framework to define disease heterogeneity to guide the empirical treatment of febrile illness in resource poor settings.
- Completed cost-effectiveness studies of amongst others the use of artesunate in severe malaria, home-management of malaria programmes, melioidosis vaccine candidates, and markers of bacterial infection such as procalcitonin.
- Development of methods for the analysis of combined epidemiological and whole genome sequence data - initially applied to whole genome sequence data for MRSA from Thailand.
- Set up collaborations with the malaria control programs of Vietnam, Cambodia, Lao PDR, Thailand, Myanmar, Bangladesh and India to support policymakers and implementers in cost-effective malaria elimination strategy design.