As rickettsial diseases generally are easily treatable, pursuing a diagnostic research theme is of high importance. Historically, typhus has been diagnosed serologically and the Indirect Immunofluorescence Assay (IFA) remains the gold standard to date.

Ongoing diagnostic studies aim at:

We have developed new methods i.e. the loop-mediated isothermal PCR assays (LAMP), and contributed in evaluating/validating rapid diagnostic tests (RDTs) and ELISA based assays. We will continue to prospectively assess the diagnostic accuracies of various diagnostic methodologies in the future.